The Andromeda Galaxy is one of the 3 galaxies that make up the Local Group. The High Guard ship Andromeda Ascendant was named after it. It was known to possess twin black holes at the center of its two cores which Hasturi called Scylla and Charybdis. ("It Makes a Lovely Light")
- Baltria: a planet powered by the Gol-Rashen, a very powerful source of energy.
- Birrin: a planet attacked by Magog Satellite Ships, killing all of the settlers.
- Brandenburg Tor: Commonwealth planet invaded by the Magog.
- Enga's Redoubt: the homeworld of the Drago-Kazov Pride.
- Helios IX: a prison planet that Dylan and Rommie were sent by the planet Arazia.
- Herodotus: Kalderan colony world destroyed by the Pax Magellanic.
- Makrai VII: the Makra homeworld.
- Midden: Tyr Anasazi crashed on this planet after he stole the remains of Drago Museveni.
- Tarn-Vedra: the Vedran homeworld.
- Ugroth: original homeworld of the Perseids.