The Milky Way galaxy is one of the galaxies that make up the Local Group.
- Acheron: High Guard Lancer base and logistics center. Seized by the Drago-Kazov Pride.
- Arazia: Planet that imprisoned Dylan Hunt and Rommie on Helios IX.
- Arzama II: A world belonging to the Than Hegemony.
- Castalia: The Castalian homeworld.
- Diphda V: Planet loyal to the Free Trade Alliance.
- Dyhedra III: A former resort destination that was seized by the Magog and destroyed by a Nova bomb.
- Earth: The Human homeworld.
- Fountainhead: The historical homeworld of the Nietzschean people.
- Hephaistos IV: location of first battle of the First Systems Commonwealth Civil War.
- Infinity Atoll: Host of the famous Pan Galactic Surfing Championship.
- Kalderash: The Kalderan homeworld located in the Lesser Magellanic Cloud
- Machen Alpha
- Xinti: a Perseid settlement and former center of learning during the Commonwealth era.